Nausea. Theseside effectscan range from being mild tosevere. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Injectafer and Feraheme are both brand-name drugs. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Its caused by your body not having enough iron, which is needed to make hemoglobin. If you have questions about using Injectafer in a child, talk with your doctor. (See also Notes section.). In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ They can recommend if this is safe for you to do. You can also write a reminder on your calendar. This website is intended for use by US healthcare professionals only. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. The body cannot metabolize such a high dose fast enough, so it ends up affecting a part of the body it wasnt intended to, such as the stomach. The Injectafer dosage your doctor prescribes will depend on your body weight. Tell all of your health care providers that you take Venofer. The Role of Genetics in Multifactorial Disorders, The Power of DNA Testing and Predictive Medicine, A Guide to Genome Explorer (Free Version), Whole Genome Sequencing in As Little As Three Weeks, What Diseases Can Be Detected Through Genetic Testing, Breast Cancer Genetic Testing: Pros and Cons, At Home Genetic Testing for Breast Cancer, DNA Tests for Breast Cancer Genetic Testing, What to Do When Medicines Have Side Effects, Blood Type and COVID: Infection Risk and Severity, Where Can I Get My Blood Type Checked for Free, How to Find Biological Father Through DNA. (A class of medications describes a group of drugs that work in the same way.). Spacing your Injectafer doses out at least 7 days helps to reduce your risk of side effects. Brand-name medications usually cost more than generics. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. Venofer treatment may be repeated if iron deficiency reoccurs. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. Terminal half-life ranges from 7 to 12 hours. You will need to talk about the benefits and risks to you and the baby. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. taste impairment. There isnt a known interaction between Injectafer and alcohol. Details. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Throw away unused or expired drugs. This site is intended for use only by US patients. These include: Note: For more information about the potential negative effects of Injectafer, see the Injectafer side effects section above. What is the latest research on the form of cancer Jimmy Carter has? Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. There are currently no generic forms of either drug. Back pain. Injectafer begins working as soon as it enters your body. However, some people can experienceside effectsfor much longer - days, months, or indefinitely. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. But for other people, their anemia may come back after Injectafer treatment. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Heres some detail on certain side effects this drug may cause. You may also report side effects at https://www.fda.gov/medwatch. You should always consult your doctor or another healthcare professional before taking any medication. People with IDA have low blood levels of hemoglobin. I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. Possibleside effectsareweight gainand suicidal thoughts. Most people will metabolize medication by half every time it circulates the body. These people may lose weight as their anemia improves because theyre more active. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). 5 0 obj Its not known if Injectafer is safe to use during pregnancy. If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. Health careproviderscan provide information on how longside effectslast by checking amedication guide. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). Theseside effectsmay last as long as they are undercancer treatment. This medication is given by injection into a vein as directed by your doctor. Injectafer helps to treat IDA by providing an iron infusion directly into your body. This is not a complete list of side effects and others may occur. There may be drug take-back programs in your area. Theyll likely have you stop taking the pills while youre using Injectafer. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. WebMD provides common contraindications for Venofer Vial. For some people, it may be OK to continue taking a multivitamin that contains iron. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. Its possible to get rid of or reduce the severity ofside effects. Does Venofer Vial interact with other medications? Available for Android and iOS devices. These lists contain examples of serious side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). Keep all regular medical and laboratory appointments. Drug interactions may change how your medications work or increase your risk for serious side effects. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. (A medication class describes a group of drugs that work in the same way.). Hemoglobin is a protein thats found in your RBCs. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. People from different ethnic backgrounds process medications differently. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. Some drugs may have another patient information leaflet. You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. But keep in mind that in this study, delayed allergic reaction only occurred in one person. Is the ketogenic diet right for autoimmune conditions? This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. reese0809 1 yr. ago. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: . For more information about Injectafers approved uses, see the section Injectafer uses below. However, to be safe, tell your doctor or pharmacist about all prescription, over-the-counter, and other drugs you take before taking Injectafer. Many patients with kidney disease cannot get enough iron from food and require injections. These side effects can range from being mild to severe. (And Injectafer is used to treat IDA.) In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. With slow IV injection, the drug is given as a single, slow injection into your vein. (A generic drug is an exact copy of the active drug in a brand-name medication.) Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). And this person had gotten their first dose of the drug without having an allergic reaction. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. Consult your doctor before breast-feeding. Also tell them about any vitamins, herbs, and supplements you use. Side effects from HRT depend on a number of factors: One of the most commonly used tests to monitor IDA is the hemoglobin test. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. experience severe side effects, please seek medical attention right away and notify the ordering physician. Injectafer contains the active drug ferric carboxymaltose. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. Its not known if Injectafer is safe to take during pregnancy. You may also need to monitor your blood pressure at home. As with all medications, the cost of Injectafer can vary. Learn how to store and discard medical supplies safely. pain or burning at the injection site. And this can affect how well those parts of your body are able to work. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. Side effectsare uncomfortable reactions to medications or drugs. How is Venofer (iron sucrose) given? This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. Fortunately, knowing how longside effectslast can help those suffering know what to donext. Cardiovascular health: Insomnia linked to greater risk of heart attack. Low blood pressure. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Other drugs may interact with iron sucrose, including prescription and over-the-counter medicines, vitamins, and herbal products. Evenbirth controlcan lead to severeside effectslike bloodclots. Yes, in some cases it may. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Keep all drugs out of the reach of children and pets. With IDA, you have anemia (low red blood cell level) thats due to not having enough iron in your body. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. 4 0 obj Below are examples of these side effects. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. Precautions. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. What are the side effects of Venofer? Injectafer isnt a medication that youll take regularly on a schedule. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. Version: 7.01. * Sex and gender exist on spectrums. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. other treatments you receive, you will need to go back for several treatments with Venofer. And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. Any long-term side effects/dangers from iron infusions? The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. Other drugs are available that can treat iron deficiency anemia (IDA). Last updated on Feb 20, 2023. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. <> Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. I hope you found answers and are feeling better now. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). dizziness. Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. This allows them to manage any side effects that you may have following your dose. These side effects may include constipation and diarrhea. If you notice other effects not listed above, contact your doctor or pharmacist. This may lead to the person needing a higher dose compared to someone who is muchsmaller. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Back pain. We cancelled my 5th because of the reaction. Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. You should not receive Venofer if you have known allergies to iron sucrose. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. These symptoms can include: While youre taking Injectafer, your doctor will monitor your phosphorus levels if youre at risk for hypophosphatemia. Check with your pharmacist if you have questions about the best way to throw out drugs. People with IDA have low blood levels of hemoglobin. treatment schedule in further detail. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. Injectafer infusions are given over a period of at least 15 minutes. Tell your doctor about the allergy and what signs you had. 3 0 obj Phosphorus is an electrolyte that your body needs in order to make energy. Brandon ColbyMD, a medical expert specializing in preventive medicine and clinicalgenomics. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. There are different types of anemia, but IDA is the most common type. But the length of time that this may take varies from person to person. Mild side effects of Injectafer can include:*. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. Selected from data included with permission and copyrighted by First Databank, Inc. The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established. However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. Generics tend to cost less than brand-name drugs. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. 2023 Medicine.com All rights reserved. Daiichi Sankyo, Inc., the manufacturer of Injectafer, offers a program called injectconnect, which may help lower the cost of the drug. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. Blood tests may be needed to check for unwanted effects. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. You may report side effects to Health Canada at 1-866-234-2345. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. However, Injectafer has been studied for use in children with iron deficiency anemia (IDA). stream It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Injectafer isnt available in a generic form. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. (A generic drug is an exact copy of the active drug in a brand-name medication.). One study of just under 5000 HRT users found that 43% were affected. Serious side effects should be reported to a physician and/or PharmD for medical advice. This medicine may cause serious types . Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. They can tell you about other medications that may work well for you. They can recommend appropriate treatment options. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). %PDF-1.3 Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. Cancer patients who have anemia and are taking an ESA. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. This gives a total cumulative dose of 1,500 mg of Injectafer. Depending on your anemia symptoms, your weight changes may be different than those described here. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. Both Injectafer and Venofer belong to a class of medications called iron replacement products. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Do not flush down a toilet or pour down a drain unless you are told to do so. Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. And this could lead to weight gain, if they increase their food intake. Its not known whether its safe to breastfeed while youre taking Injectafer. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. No, Injectafer itself wont make you gain weight. Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? Youll receive doses of Injectafer from a healthcare professional at a medical facility. endobj So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Drug class: Iron products. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. It's a more immediate treatment than supplements or dietary changes. Last updated August 20, 2020. Here we look at how Injectafer and Feraheme are alike and different. Which tests can diagnose iron deficiency anemia? Do not flush medications down the toilet or pour them into a drain unless instructed to do so. If your symptoms or health problems do not get better or if they become worse, call your doctor. (Hemoglobin is a protein thats found in red blood cells.). Venofer is given as an infusion into a vein. For example: Say you weigh 105 pounds (about 48 kilograms). It belongs to a class of medications known as iron replacement products. There have also been reports of serious allergic reactions to Venofer. Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] I actually was constipated after my 3rd but didn't think anything of it. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. Youll receive doses of either drug by a healthcare professional at a medical facility. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Following an LSD trip, users may experience a sort of 'comedown.'. In the US - Call your doctor for medical advice about side effects. And these two doses need to be separated by at least 7 days. An iron infusion is a way to increase the body's iron levels quickly. Your doctor will determine the best dosage to fit your needs. chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes Effectiveness of Injectafer compared with iron thats taken by mouth. Why is the range so wide? It is given into a vein for a period of time. . But so far I feel better than before the infusion. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. They have been a god send. In clinical studies, people who took Injectafer had their hemoglobin level improve as early as 35 days after receiving treatment. I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. 2. If you have questions about side effects, call your doctor. This survey is being conducted by the WebMD marketing sciences department. Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). This is not a complete list of side effects and others may occur. Ask your doctor or healthcare provider if Venofer is the right choice for you. <> These are not all of the side effects that may occur. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. With anemia, you have a low level of red blood cells (RBCs) in your body. Then the study was split into the following two groups, which are discussed below. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft).